Differences between cellular integration sites of transcribed and nontranscribed Rous sarcoma proviruses
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منابع مشابه
Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus
We have derived a line of A431 human tumor cells infected with Rous sarcoma virus (RSV). The infected cells contain the RSV-transforming protein, pp60src, which has characteristic tyrosine specific protein kinase activity. As in other RSV-transformed cells, a 36,000-dalton protein is phosphorylated in RSV-infected A431 cells. Addition of epidermal growth factor (EGF) to the cells induces furthe...
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We used an in vitro nuclear runoff replication assay to analyze the direction of replication of the active and inactive histone H5 genes in avian cells. In embryonic erythrocytes the transcribed histone H5 gene displayed sensitivity to endogenous nuclease cleavage. In contrast, this gene was insensitive to endogenous nuclease digestion under the same conditions in nuclei of the lymphoblastoid c...
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Chickens carrying primary sarcomas induced by SchmidtRuppin Rous virus were studied for possible cellular immunity against the tumor-specific transplantation antigens of those tumors by use of the colony inhibition test. The thymus cells of 7 out of 8 tested chickens were found to reduce signifi cantly the colony formation of Rous sarcoma cells while they had no similar effect on other types of...
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When the endogenous polypurine tract (PPT) of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z was replaced with alternate retroviral PPTs, the fraction of unintegrated viral DNA with the normal consensus ends significantly decreased and the retention of part of the PPT significantly increased. If the terminus of the U3 long terminal repeat (LTR) is aberrant, RSV integrase can correctly pro...
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SHIPMAN, CHARLES, JR. (Indiana University School of Medicine, Indianapolis), AND ALVIN S. LEVINE. Selective response of the Japanese quail to various strains of Rous sarcoma virus. J. Bacteriol. 92:161-163. 1966.-The Bryan "high-titer," CarrZilber, Harris, Prague, Schmidt-Ruppin, and "29" strains of Rous sarcoma virus were used to initiate tumors in the Japanese quail (Coturnix coturnix japonic...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1991
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.65.1.461-463.1991